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Unclustered monoclonal antibodies (MoAbs)
| Unclustered MoAbs | |
|---|---|
| TdT | Terminal deoxynucleotidyl transferase B-ALL, T-ALL, weak in some AML |
| PD1 | Progammed cell death protein-1 T-cell lymphomas in particular those with T-follicular-helper-phenotype |
| Ig† | Immunoglobulin B-cell receptor |
| MPO† | Myeloperoxidase maturing myeloid (strong), monocytes (weak) |
| HLA-DR | Class II antigen blasts, monocytes, B-lymphocytes, activated T-lymphocytes |
| FMC7 | epitope of the CD20 molecule, B-NHL, B-PLL, negative/weak on CLL |
| Ki67 | proliferation marker (G1, G2, S phase and mitosis), negative in G0 phase. Same as MIB-1 used in formalin fixed tissue. |
| †specific for the lineage (CD19 used as a specific early B-cell marker in MPAL in the WHO classification) | |